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UID:220e900493f42c256242a93fdbde399e
CATEGORIES:Mathematical Physics Seminar
CREATED:20240529T144644
SUMMARY:Webinar: Jane Kondev - The Scale Invariant Cell
LOCATION:Zoom
DESCRIPTION:<p style="text-align: center; background: white;"><strong>MATHEMATICAL PHYS
 ICS WEBINAR<br> RUTGERS UNIVERSITY</strong></p><p style="text-align: center
 ; background: white;"><strong>__________________________________________</s
 trong>&nbsp;</p><p style="text-align: center; background: white;"><strong>J
 ane Kondev– Brandeis University</strong></p><p style="text-align: center; b
 ackground: white;">Wednesday,&nbsp;June 12th,&nbsp;<strong>10:45AM EDT&nbsp
 ;(Zoom meeting starts at 10:30 EDT)</strong></p><p>&nbsp;</p><p style="text
 -align: center; background: white;"><strong>The Scale Invariant Cell</stron
 g></p><p style="background: white;"><strong>&nbsp;</strong></p><p style="ba
 ckground: white;">Dr. Gulliver noticed 150 years ago that the size of the c
 ell's nucleus is proportional to the size of the cell. Scaling of other org
 anelles, such as the mitotic spindle, the nucleolus, mitochondria, etc., wi
 th cell size has been reported over the years. These observations suggest a
 n engineering problem that cells face: How do living cells measure their ow
 n size and incorporate this information in the process of organelle assembl
 y? I will review theoretical ideas and experiments that support a simple me
 chanism for detecting the cell volume, which is based on depleting the pool
  of building blocks in the process of assembly. In some cases the cell is f
 aced with the challenge of measuring its linear dimensions to control the l
 ength of a self-assembling &nbsp;filamentous structure, in which case the l
 imiting pool mechanism does not work. I will describe some of our recent ex
 periments and related theory that address the question of how cells measure
  length.</p>
DTSTAMP:20260828T150904
DTSTART;TZID=America/New_York:20240612T104500
DTEND;TZID=America/New_York:20240612T114500
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