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BEGIN:VEVENT
UID:7f48a4302fe860e2f6765a94164e17e6
CATEGORIES:Mathematical Physics Seminar
CREATED:20220721T105628
SUMMARY:Viruses, Immunity, and Vaccines
LOCATION:Zoom
DESCRIPTION:<p style="text-align: center;">Infectious disease-causing pathogens have pl
 agued humanity since antiquity, and the COVID-19 pandemic has been a vivid 
 reminder of this perpetual existential threat. Vaccination has saved more l
 ives than any other medical procedure, and indeed, effective vaccines now p
 romise to control the COVID-19 pandemic. However, we do not have effective 
 vaccines against rapidly mutating viruses, such as HIV; nor do we have a un
 iversal vaccine against seasonal variants of influenza or SARS-CoV-2 varian
 ts that may evolve in the future. The ability to develop effective vaccines
  that protect us from highly mutable viruses will help create a more pandem
 ic-resilient world. In this talk, I will describe how by bringing together 
 approaches from statistical physics, virology and immunology, progress is b
 eing made to address this challenge. I will briefly summarize work that aim
  to define the mutational vulnerabilities of mutable viruses. Then, I will 
 focus on approaches that aim to design vaccines and immunization strategies
  that elicit immune responses that can target these vulnerabilities. The ap
 plication of these fundamental concepts to HIV and influenza vaccines will 
 be discussed.&nbsp;</p>
CONTACT:Arup K. Chakraborty - Ragon Institute of MGH, MIT &amp; Harvard
DTSTAMP:20260829T144600
DTSTART;TZID=America/New_York:20220727T104500
DTEND;TZID=America/New_York:20220727T114500
SEQUENCE:0
TRANSP:OPAQUE
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