Seminars & Colloquia Calendar

Download as iCal file

Mathematical Physics Seminar

Webinar: Edo Kussell: Evolutionary advantage of cell size control

Location:  Zoom
Date & time: Wednesday, 15 May 2024 at 10:45AM - 11:45AM

MATHEMATICAL PHYSICS WEBINAR

-------------------------------------------------------

Edo Kussell – New York University

Wednesday, May 15th, 10:45AM EDT 

 

Evolutionary advantage of cell size control

Molecular mechanisms that control cell growth and division enable bacteria and other microorganisms to maintain a narrow range of cell sizes within a population. While the control of cell size is ubiquitous in biology, the evolutionary benefit of maintaining a characteristic cell size is not understood in detail. In this talk, I will analyze the advantage of cell size control strategies in growing populations of bacteria using a transfer operator formulation. I will discuss how mortality can select for accurate cell size control, and derive an analytical expression for the optimal cell size. I will show that epigenetic heritability of cell size gives bacteria an evolutionary advantage by enabling selection to act on the distribution of cell sizes in a population to reduce mortality rates. I will discuss these results in the context of experimental measurements in bacteria, and their implications for the evolution of size control mechanisms.

Special Note to All Travelers

Directions: map and driving directions. If you need information on public transportation, you may want to check the New Jersey Transit page.

Unfortunately, cancellations do occur from time to time. Feel free to call our department: 848-445-6969 before embarking on your journey. Thank you.