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Mathematical Physics Seminar

Uri Alon - Aging has nearly universal quantitative patterns

Location:  zoom
Date & time: Wednesday, 10 January 2024 at 10:45AM - 11:45AM

Uri Alon – Weizmann Institute of Science

Wednesday, January 10th, 10:45AM EST (Zoom meeting starts at 10:30 EDT) 

Aging has nearly universal quantitative patterns

 

We explain them using a stochastic ode for damage production and removal, deduced from experiments on damage dynamics in mice and in individual bacteria, the latter done by us. This simple model explains a wide range of phenomena in human aging and age related diseases. The talk will assume no knowledge in biology.

References:

Yang, Y., Karin, O., Mayo, A. et al. Damage dynamics and the role of chance in the timing of E. coli cell death. Nat Commun 14, 2209 (2023). https://doi-org.ezproxy.weizmann.ac.il/10.1038/s41467-023-37930-x

Compression of sickspan by interventions that steepen the survival curve
Yifan Yang, Avi Mayo, Tomer Levy, Dan Jarosz, Uri Alon
bioRxiv 2023.10.04.560871; doi: https://doi.org/10.1101/2023.10.04.560871

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